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On 14 August, a study was published by Pre-Prints, a platform that allows studies not yet peer-reviewed to be made publicly available.
The paper has coined the term “Hybrid Harms Hypothesis” to describe the compounding effects of mRNA injections and coronavirus infections, where the mRNA “vaccines” and SARS-CoV-2 interact to produce a toxic synergy.
The authors argue that mRNA injections deliver toxic spike protein, lipid nanoparticles and DNA contaminants, which can cause chronic illness, sudden deaths and excess mortality, and amplify the adverse effects of future SARS-CoV-2 encounters.
The paper notes that countries with high mRNA “vaccine” uptake have seen sustained excess all-cause mortality, with many deaths occurring in fully vaccinated or boosted people. “An analysis of 145 countries found vaccination programmes linked with up to 291% more cases and 205% more deaths than projected without them,” Nicholas Hulscher writes.
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The following is an article by Nicholas Hulscher with an introduction by Europe Reloaded.
Hulscher takes the position on “covid” and the “vaccines” that we have taken since late 2020.
This piece puts us in mind of Prof. Dolores Cahill, way back in 2020 or 2021, who understood well what was going on [See HERE and HERE, also see HERE]. To paraphrase, she said that between the covid “virus” and the injections, “they get you going in or coming out.” The orchestration of this plandemic just through the components of the bioweapon, the shots and the pattern of health harms/deaths is pretty clear by now.
Our residual question here is: If covid was a deliberately distributed bioweapon, perhaps in several waves for which there is evidence, then how do vaccinated people “get covid” in the future? Is future covid just a weakened immune system responding in certain dysfunctional ways because of the mRNA in their systems? We’re not clear about this.
Europe Reloaded Editor, 15 August 2025
Breaking Manuscript: mRNA Vaccines and SARS-CoV-2 Synergistically Fuel Global Excess Mortality and Illness
By Nicholas Hulscher, MPH, as published by Focal Points on 14 August 2025
Before we dive into the new manuscript, it’s important to understand that humanity was hit with dual biowarfare agents:
- A manufactured SARS-CoV-2 virus – the product of US-China collaboration, engineered through years of dangerous gain-of-function work.
- mRNA gene therapy “countermeasures” – conceived under DARPA’s pandemic programmes over 10 years ago.
Together, they have unleashed waves of chronic illness, sudden deaths and unprecedented excess mortality. We were told mRNA vaccines would protect us from the virus – yet mounting evidence shows they have done the complete opposite.
Now, the McCullough Foundation’s new 380-reference scientific manuscript, ‘Compound Adverse Effects of COVID-19 mRNA Vaccination and Coronavirus Infection: A Convergence of Extensive Spike Protein Harms to the Human Body’, examines how these two agents interact to produce a toxic synergy we term the “Hybrid Harms Hypothesis.”
This comprehensive work – authored by M. Nathaniel Mead, MSc, PhD; Jessica Rose, MSc, PhD; Stephanie Seneff, MSc, PhD; Claire Rogers, MSPAS, PA-C; Breanne Craven, PA-C; Nicolas Hulscher, MPH; Kirstin Cosgrove, BM, CCRA; Paul Marik, MD; and Peter McCullough, MD, MPH – details how coronavirus infections may amplify the adverse effects of prior mRNA vaccination for years, creating a sustained global health crisis marked by chronic illness, sudden deaths and persistent excess mortality.
The Five Features of the Hybrid Harms Hypothesis
1. Immunotoxic Payload
mRNA vaccines deliver:
- Spike protein – toxic whether from virus or vaccine.
- Lipid nanoparticles – highly inflammatory and immune-disruptive.
- DNA contaminants – risking genomic integration, autoimmunity and cancer.
This persistent immunotoxic burden primes the body for greater damage upon future SARS-CoV-2 encounters.
2. Whole-Body Biodistribution
The mRNA-LNP package does not remain at the injection site. It travels throughout the body, crossing the blood–brain and placental barriers and accumulating in the heart, brain, ovaries, adrenal glands and more. This means any infection can become a multi-organ assault.
3. Prolonged Spike Protein Exposure
Heavily modified for stability, synthetic mRNA can drive spike protein production for months – and in documented cases, for years. This persistence cannot be fully explained by prolonged mRNA stability or protein retention alone. A plausible mechanism is genomic integration of plasmid-derived foreign DNA – including the SV40 promoter and spike-encoding DNA – into human cells.
The spike protein itself is resistant to breakdown and can remain embedded in tissues long after injection. This creates a 2 to 3 year “Window of Vulnerability” in which each subsequent SARS-CoV-2 [“covid”] reinfection may amplify damage, layering new injury on top of existing spike-induced pathology – a process central to the Hybrid Harms Hypothesis.
4. Cumulative Exposure
Multiple mRNA doses stack up the risk. Each shot adds to the total spike burden and deepens immune dysregulation. Infections after repeated vaccination are met with altered immune programming – including IgG4 class-switching and T-cell exhaustion – impairing viral clearance and cancer surveillance.
5. Overlapping Pathophysiology
Both mRNA vaccination and SARS-CoV-2 infection can cause:
- Hyperinflammation
- Autoimmunity
- Lymphopenia
- Interferon suppression
When these mechanisms overlap, they can be additive or synergistic, making post-vaccination infections far more dangerous than either exposure alone.
Negative Efficacy Fuels Covid-19
In all eight nations shown in Figure 1, major case and death surges began only after 75% of the population was fully vaccinated – during the mild Omicron era. Large studies consistently show that mRNA injection protection fades within months, then flips into negative efficacy, where more doses mean higher infection risk. An analysis of 145 countries found vaccination programmes linked with up to 291% more cases and 205% more deaths than projected without them. These patterns point to mass mRNA vaccination as a key driver of post-rollout covid-19 waves.
Post-Vaccine Syndrome Often Masquerades as “Long Covid”
Many cases of so-called long covid since 2021 may actually be post-vaccine syndromes from covid-19 mRNA injections. Both infection and vaccination expose the body to persistent spike protein, driving overlapping symptoms across cardiovascular, neurological, autoimmune and other systems. Studies show vaccinated people often have higher spike antibody levels – and higher rates of chronic symptoms – than their unvaccinated counterparts. Misclassification of vaccine injuries as PASC [post-acute sequelae of SARS-CoV-2 infection] hides the full scope of harm and distorts the risk–benefit profile of mRNA products.
Excess Mortality and Misattribution
The epidemiological pattern is clear:
- Countries with high mRNA vaccine uptake saw sustained excess all-cause mortality even after Omicron’s lethality had sharply declined.
- Many of these deaths were logged as “covid-19” but occurred in fully vaccinated or boosted people, often months or years after their last injection.
- Mechanistically, it is plausible that prior vaccination amplified the severity of otherwise mild reinfections, leading to worse outcomes.
This systematic misattribution has obscured the real role of vaccination in post-2021 mortality. The Hybrid Harms Hypothesis provides a biologically consistent explanation for why even mild Omicron waves coincided with persistent spikes in excess deaths.
If the Hybrid Harms Hypothesis is correct, millions remain in a prolonged danger zone where each reinfection can trigger severe illness or death – a consequence of mass mRNA vaccination policy layered on top of a laboratory-engineered pathogen.
This has produced a sustained, global health crisis with no precedent in modern history – and still no accountability for those responsible. This article can only summarise the full breadth of evidence presented in the paper. Please read the full manuscript here: ‘Compound Adverse Effects of COVID-19 mRNA Vaccination and Coronavirus Infection: A Convergence of Extensive Spike Protein Harms to the Human Body’.
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Categories: Breaking News, World News
[…] mRNA vaccines not only cause covid, but post-vaccination infections are far more dangerous, a new st… […]
Dr. Lee Merritt has been claiming for years that the mRNA platform has a 20-plus year history of ultimately killing all the vaccinated animals of “Antibody Dependent Enhancement” (aka, Immune Erosion). This should stop the mRNA platform forever!
https://varjager.wordpress.com/2021/01/30/dr-lee-merritt-in-animal-studies-after-being-injected-with-mrna-technology-all-animals-died-upon-reinfection/
Del Bigtree did an excellent presentation early after the vaccine rollout showing in an easy-to-understand manner, how these shots do more harm than good, by using a “football analogy.
https://rumble.com/vg4t4h-you-dont-want-to-miss-this.html?mref=lzerp&mrefc=2
Dr. Luc Montagnier gave an interview where he said he had identified fragments of HIV insertions in these shots. This is why some report VAIDS obviously. They INSERTED the HIV intentionally!
https://rumble.com/vv7zjj-nobel-prize-winner-professor-luc-montagnier-exposes-hiv-put-in-injections.html
If every major government around the world was involved in a “practice run” on how to handle a pandemic just months prior to the COVID “pandemic”, and they ALL jumped onboard all these obvious inappropriate responses – masking, draconian lockdowns, dangerous gene therapies dressed up to look like vaccines, stopping early treatments, alienating loved ones, et cetera, perhaps it is time to look at the REAL reason they are installing a bioweapon in 80% of the human race?
B. Gate und andere zielen darauf ab, die Weltbevölkerung um Milliarden zu reduzieren…
And Trump is still out there (even recently on “Hannity”) gaslighting and brainwashing saying “everyone” thinks that “operation warp speed” was one of the best things in history. Does he really believe this, or is he being told to say it? At this point, I have to believe he really does think murdering and maiming multitudes of millions of people is the best thing since sliced bread. He did NOT “save millions of lives” with this destructive and evil technology. Not at all. It is shocking and amazing that this garbage is still, not only on the market, but being pushed as the “platform” for future so-called “vaccines” (which they are not… they are, at a minimum, gene editing injections). I believe Trump is trying to do the same thing he’s done with the Epstein crimes: Lull his worshippers to sleep and make them question everything they have witnessed happening right in front of them. Well, it’s not going to work on me and it (hopefully) won’t work on any of the readers of Expose.
I used google translate, Latin to English, I entered ‘a stra ze neca’. Guess what it came back with?
How appropriate: a road to death
Astra – stars. Seneca – place of stones. Ad – to the
It’s a Z not an S.
I entered the same spelling as you, and it came up with “do not kill the star”.
[…] THE EXPOSÉ […]
The “Hybrid Harms Hypothesis” is wrong because it is built around the false premise that “coronavirus infections” are real and that
SARS-CoV-2 exists in order to “produce a toxic synergy”.
There is no valid scientific evidence for the existence of SARS-CoV-2, or coronaviruses in general, or for the transmission of the symptoms claimed to be caused by these “viruses”. Detailed epidemiological analysis by Prof Denis Rancourt et al has proven that there was no pandemic caused by person to person spread of a pathogen. All excess deaths were iatrogenic during the “first wave” and then subsequently due to the highly toxic and lethal injections.
The lab leak “gain of function” nonsense is the officially sanctioned limited hangout narrative that is designed to keep people believing in the deadly virus psy-op.
It’s important to understand that the authors of this manuscript are making money from treating “spikeopathy” and sell detox protocols for this purpose. This will include many who did not get the toxic shots but were given a false diagnosis of “covid” and so have never actually come into contact with spike protein.
Dr. Peter McCullough has been publicly challenged regarding his pseudoscientific beliefs in virology but was not able to provide a satisfactory response. Presumably its difficult to grasp simple logic and reason or consider the evidence that virology is a fraudulent pseudoscience when large amounts of money are at stake.
It has been isolated.
https://academic.oup.com/cid/article/71/9/2428/5811871
“Besides fulfilling the Koch’s postulates by reproducing the clinical and pathological changes of pneumonia by virus challenge, recovery of pure virus from infected tissues, and detecting the rise of SARS-CoV-2–specific neutralizing antibody, we also demonstrated virus transmission by close contact between the challenged index hamsters to the naive contact hamsters housed in the same cages.”
And it’s synthetic
https://www.biorxiv.org/content/10.1101/2022.10.18.512756v2
This is the definition of isolate:
(Chemistry) To separate (a substance) in pure form from a combined mixture. (Microbiology) To separate (a pure strain of a microorganism or virus) from a mixed culture.
This is the methods section from the paper you posted:
“SARS-CoV-2 was isolated from the nasopharyngeal aspirate specimen of a patient with laboratory-confirmed COVID-19 in Hong Kong [15]. The plaque purified viral isolate was amplified by 1 additional passage in VeroE6 cells to make working stocks of the virus as described previously [15].”
This is the cited reference 15:
“Improved Molecular Diagnosis of COVID-19 by the Novel, Highly Sensitive and Specific COVID-19-RdRp/Hel Real-Time Reverse Transcription-PCR Assay Validated In Vitro and with Clinical Specimens.”
Perhaps you can specifically point to the bit where the “virus” was separated from all other things? I have looked and cannot find it. Virologists misuse the term “isolate” because they are pseudoscientific fraudsters.
The argument about purification relates to 19th Century microbiological theory that does not apply to viruses.
So it’s not a mandatory requirement.
It’s 2025, and viruses have been cloning for 20 years.
Absolute nonsense. The scientific method should still apply in 2025. The scientific method involves testing an independent variable against dependent variables in properly controlled studies. In the case of virology the independent variable would be an isolated and purified particle that they claim causes disease as the starting point for any experiment. Show me one study in which virologists have followed the scientific method.
Maybe you’ve never heard of Baric and bioinformatics.
You can start here
https://dspace.mit.edu/bitstream/handle/1721.1/39652/Baric%20Synthetic%20Viral%20Genomics.pdf
and get here
https://berthub.eu/articles/posts/reverse-engineering-source-code-of-the-biontech-pfizer-vaccine/
https://pmc.ncbi.nlm.nih.gov/articles/PMC7036342/
https://journals.asm.org/doi/10.1128/jvi.00543-20
https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0247524
https://viroliegy.com/
I reply with one sentence: “There is a huge gap between the fact that there is no absolute certainty and the fact that the virus does not exist”.
There is no valid scientific evidence for the existence of viruses. The definition of a virus being a replication competent disease causing transmissible sub-microscopic particle. Prove me wrong.
“The definition of a virus beeing a replication competent disease causing transmissible sub-microscopic particle.”
This is what happened in 2020.
You answered yourself.
Absence of proof is not proof of absence.
https://drsambailey.com/a-farewell-to-virology-expert-edition/
It does not matter if you believe in the virus or not, they used that (or our ignorance of viruses) as the foundation to push, prod, and mandate most of the human race into being injected with a dangerous, toxic concoction that causes a TON of damage. 80% of the U.S. took one shot and 70% took two or more of these COVID shots. These shots includes Graphene Oxide (GO) and lipid nanoparticles (which are probably magnetic, which then makes the GO magnetic as well).
Many countries used the time of the COVID lockdowns to install these HUGE 5g towers. Now, go and Google how Graphene Oxide reacts when excited by 4g and 5g. This is truly frightening.
*** https://www.bing.com/videos/riverview/relatedvideo?q=how+Graphene+Oxide+is+excited+by+4g&refig=b7128f3f35d642798d92d3ee7f0c9edb&mkt=en-us&ru=%2fsearch%3fq%3dhow%2bGraphene%2bOxide%2bis%2bexcited%2bby%2b4g%26form%3dMSNSB1%26refig%3db7128f3f35d642798d92d3ee7f0c9edb%26mkt%3den-us&mmscn=vwrc&mid=EE7BCF30B7D6ABD1067AEE7BCF30B7D6ABD1067A&FORM=WRVORC&ntb=1&msockid=f75a41ec86b511f0bdca10fd86f4e163
In addition, you need to realize that just prior to the 2020 COVID pandemic, they started putting GO in the flu shots in the U.S. as well. And no doubt, they also put MORE of it in the shots for the elderly, claiming their response to regular vaccines does not work without EXTRA crap in the shots so they can supposedly get a “proper” response.
Up until recently, you could go on the NEXRAD website and see that all these HUGE “weather towers” that have been set up across the U.S. over the last decade or so. Now, over the lest few years, they have been emitting intense amounts of radiation in a well-planned and orderly manner in the middlle of the night, going East to West – for the WHOLE night, when no one is watching or paying any attention what so ever. It radiated out from the center of the tower, overlapping the next tower’s field of radiation – hundreds of times every night; maybe even thousands of times every night. This was happening, probably for no doubt for YEARS, and no one realized what was happening, who was doing this, and what the implications of this would be – probably FOR YEARS!
So, take all the ignorant, trusting, naive people, not just here, but ALL AROUND THE WORLD, inject them with minute magnetic shards of Graphene Oxide. Or, as German Scientist, Dr. Andreas Noack – who died in police custody shortly after posting a video about this – claimed early after the vaccine rollout, these shots contain not just GO but Graphene Hydroxide – or as he said minute GO so tiny that it would shred the blood vessels at the capillary level and would not even be detectible by a Pathologist (in the event some country actually allowed autopsies during the pandemic).
Now, combine that information with these HUGE towers emitting radiation ALL NIGHT LONG FOR YEARS. Add in most of the population having Graphene Oxide and Graphene Hydroxide and the new 5g towers interacting with everyone who lives or even travels within their vicinity (and some claim they are putting these huge 5g towers near schools, including elementary schools).
It is irrelevant whether you believe in viruses or not. Every time the world upgrades from 1g to 2g to 3g to 4g and now, to 5g, we get a “pandemic”. But now, we have SCIENTIFIC TECHNOLOGY and they are throwing in “fragments of HIV insertions” in the virus (per Nobel Laureate Dr. Luc Montagnier), and your chance of catching COVID increases dramatically with every shot you took.
https://rumble.com/vv7zjj-nobel-prize-winner-professor-luc-montagnier-exposes-hiv-put-in-injections.html
And Dr. Montagnier also talked about how he had twenty-one patients who died of a fast-progressing Creutzfeldt-Jakob Disease (CJD) within five months of their 2nd COVID shots, so we knew that these shots would cause an increase in prion diseases as well. Prion diseases include CJD, Alzheimer’s, Parkinson’s, and Lewy Body Disease.
Throw in the government telling everyone to stay home until you were seriously ill – then present yourself to the Emergency Room when they got sick, instead of the usual recommendation of “go to your doctor and get treated immediately when you get sick”, the hospital’s only CDC approved response was “Remdesivir and a Ventillator” (which Fauci used to kill a lot of AID’s patients during the AIDs pandemic), and hospitals being financially rewarded for killing people as long as they put “Death from COVID” (regardless of what they died from) on the Death Certificate.
According to Dr. Lee Merritt, the mRNA platform was a failed platform with a 20-year history of killing all the vaccinated animals of “Antibody Dependent Enhancement” (aka, Immune Erosion).
The Spike Protein, according to Dr. Geert vanden Bossche, is the most DANGEROUS of all proteins, which was why scientists have avoided using it previously.
I guess what I am saying is that they intentionally used the most dangerous things. And the CDC, FDA, pharmaceutical company executives, the WHO and all other world health agencies, the media, the health groups (including heads of hospitals, doctors and nurses) were all in collusion.
This is bigger than just an “elite group”, this is people at EVERY level in the most important and trusted positions in the world – all colluding because they… What, wanted to line their pockets with gold? Seriously?
It appears that way. Money over humanity and the future of our species? Because it appears this is integrating into everyone’s DNA. No one will be human anymore, not after this? They created these shots so they shed from vaccinated to unvaccinated!
https://therebelpatient.substack.com/p/japan-declares-a-state-of-emergency?r=6niza&utm_medium=ios&triedRedirect=true
[…] RNA vaccines not only cause covid, but post-vaccination infections are far more dangerous, a new stu… On 14 August, a study was published by Pre-Prints, a platform that allows studies not yet peer-reviewed to be made publicly available….The paper notes that countries with high mRNA “vaccine” uptake have seen sustained excess all-cause mortality, with many deaths occurring in fully vaccinated or boosted people. “An analysis of 145 countries found vaccination programmes linked with up to 291% more cases and 205% more deaths than projected without them,” Nicholas Hulscher writes. […]